Inhalation Toxicology

Inhalation toxicity can be described as the adverse effects in total that are caused by a substance that is capable of being inhaled following a single uninterrupted exposure by inhalation over a short-period of time (24 hours or less). The toxic characteristics of a substance is determined by different steps and among them determination of acute toxicity is the initial step in the assessment and evaluation of that substance that may be inhaled such as a gas, volatile substance, or aerosol/particle. It provides information on health hazards that are likely to arise from short-term exposure via inhalation route. Data from an acute study may serve as a basis for classification and labeling. Inhalation toxicity is by different routes and they are oral, dermal or inhalation route. 

  • Reproductive inhalation
  • Neonatal inhalation
  • Anti-asthmatic inhalation
  • Immunologic sensitization via inhalation
  • Intranasal Inhalation
  • Intratracheal Inhalation
  • Anti-asthmatic efficacy
  • Acute to chronic toxicity, plus carcinogenicity
  • Radiolabeled aerosol studies
  • Nose-only, oronasal and head-only

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